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The compounding area is also to be designed, arranged, used, and maintained to prevent adventitious cross-contamination.Areas used for sterile preparations are to be separated and distinct from the nonsterile compounding area (see Compounding areas are to be maintained in a clean and sanitary condition.
Adequate washing facilities are to be provided, including hot and cold water, soap or detergent, and air driers or single-service towels.
Sewage, trash, and other refuse in the compounding area is to be disposed of in a safe, sanitary, and timely manner.
Equipment and accessories used in compounding are to be inspected, maintained, cleaned, and validated at appropriate intervals to ensure the accuracy and reliability of their performance. Stability is defined as the extent to which a preparation retains, within specified limits, and throughout its period of storage and use, the same properties and characteristics that it possessed at the time of compounding.
See the table The compounder must avoid formulation ingredients and processing conditions that would result in a potentially toxic or ineffective preparation.
Over my 30 year carreer I’ve reviewed medication storage locations in about 500 hospitals.
A calendar with someone’s signature might be enough to convince the manager that the inspection happened. The container used depends on the physical and chemical properties of the compounded preparation.Containerdrug interaction is to be considered with substances such as phenolic compounds and sorptive materials (e.g., polypeptides and proteins).However, a compounder may refer to the literature or to the manufacturer for stability information.The compounder may also refer to applicable publications to obtain stability, compatibility, and degradation information on ingredients.Compounders engaging in compounding should have to continually expand their compounding knowledge by participating in seminars, studying appropriate literature, and consulting colleagues.Tags: Adult Dating, affair dating, sex dating