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Pigs offer a unique opportunity to identify genes or genomic regions encoding quantitative trait loci (QTLs) since they have been through recent and strong selective sweeps targeted at phenotypes to improve agricultural performance and disease resistance. The pig whole genome sequencing project has been launched in the early of 2006 initiated by the Swine Genome Sequencing Consortium (SGSC) (

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Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 W. Alternative splicing: Increasing diversity in the proteomic world.

Gregory Dr., Urbana, IL 61801, USA How to cite this article: Chen K, Baxter T, Muir WM, Groenen MA, Schook LB. Available from pig, a representative of the artiodactyla clade, is one of the first animals domesticated, and has become an important agriculture animal as one of the major human nutritional sources of animal based protein.

Domestication also provides rapid phenotypic evolution through artificial selections. A somatic cell hybrid panel for pig regional gene mapping characterized by molecular cytogenetics.

Pig domestication has resulted in highly modified morphological architectures and has caused several major changes in physical types, e.g.

In addition to providing important evolutionary information, the availability of the pig whole genome sequence will contribute toward revealing the molecular mechanisms controlling phenotypes and play an increasingly significant role in pork production, by integrating 'omics' techniques and bioinformatics tools to reduce the incidence of disease and respond more rapidly to the changing demands of consumers. scrofa is one of the most globally widespread mammalian species.

It has long been assumed that the force driving evolution was domestication and natural selection.

Keywords: Alternative splicing, Association mapping, Domestication, Genetic diversity, Genome sequencing, QTL, Selection, Selective sweeps, SNPs The recent completion of the human genome sequence provides a starting point for understanding genetic complexity and elucidating genetic variations contributing to diverse traits and diseases. Absence of correlation between DNA repair in ultraviolet irradiated mammalian cells and life span of the donor species.

Pigs are even-toed ungulates belonging to the order artiodactyla, an order phylogenetically closer to primates than rodentia [1]. scrofa, a wild boar, approximately 9,000 years ago in multiple regions of the world [2-4].

Department of Animal Sciences, University of Illinois at Urbana-Champaign, 1201 W. Department of Animal Science, Purdue University, West Lafayette, Indiana 47907-1151, USA3.

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